Mammalian Methylation Data Browser
An open cross-species DNA methylation resource - browse, select and download the datasets behind the largest comparative methylation study ever assembled.
Open the Data BrowserWhy a Cross-Species Atlas?
Nature has evolved mammalian species of greatly differing lifespans. To resolve the relationship of DNA methylation with maximum lifespan and phylogeny, researchers performed a large-scale cross-species unsupervised analysis.
Comparative studies across many species make it possible to identify epigenetic correlates of maximum lifespan and of other traits - signals that simply cannot be seen from any single species in isolation.
What You Can Do With It
- View and select key datasets for further research
- Download the underlying data from GEO
- Test available epigenetic clocks on each species
- Compare methylation signatures across the mammalian phylogeny
Accessing the Data
Data from the Mammalian Methylation Consortium is downloadable from GEO, and a browser is available below to view and select key datasets for further research. Beyond access to the methylation data itself, additional tools are being made available to enable testing of available epigenetic clocks on each species.
mydata.clockfoundation.orgSource Publication
Haghani A, Li CZ, Robeck TR, Zhang J, Lu AT, Ablaeva J, et al. DNA methylation networks underlying mammalian traits. Science 2023;381:eabq5693.
Questions About the Data?
Please contact a corresponding author on the paper, or reach the Clock Foundation directly.
info@clockfoundation.org