Mammalian Methylation Data Browser
Nature has evolved mammalian species of greatly differing lifespans. To resolve the relationship of DNA methylation with maximum lifespan and phylogeny, researchers performed a large-scale cross-species unsupervised analysis. Comparative studies in many species enables the identification of epigenetic correlates of maximum lifespan and other traits.
Data from the Mammalian Methylation Consortium will be downloadable from GEO and also a browser is available at the link below to view and select key datasets for further research:
Beyond access to methylation data, additional tools will be made available to enable testing of available epigenetic clocks on each species. The full data are now available at the link above. The source publication in Science is the following:
Haghani A, Li CZ, Robeck TR, Zhang J, Lu AT, Ablaeva J, et al. DNA methylation networks underlying mammalian traits. Science 2023;381:eabq5693. https://doi.org/10.1126/science.abq5693.
A free link to view and download the full text paper is here.
For any questions, please contact a corresponding author or us directly at the Clock Foundation at [email protected].
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